Isabel Del Pino
Isabel Del Pino
Affiliation: Prince Felipe Research Center
Fields or areas of research Biomedicine , Neuroscience
CIDEGENT distinguished investigator since 2020. Principal Investigator of the Neural plasticity lab in Valencia (Prince Felipe Research Center, CIPF).
PhD in Biochemistry, Max-Planck-Institute for Brain Research in Frankfurt am Main (Germany) and postdoc positions at the Instituto de Neurociencias UMH-CSIC in Alicante (Spain), King´s College London (UK) and Neurocentre Magendie in Bordeaux (France). Awarded with an Initiative d´excellence (IdEx) Fellowship at the University of Bordeaux and a Young IBRO Regions Connecting Award as well as IBRO-PERC/FENS, SRUK-CERU travel grants.
For almost a decade, my research has been focused on understanding the neurobiological basis of learning and memory in health and disease. My research on the molecular and cellular determinants of complex behaviour has been relevant to better understand the neurobiological substrate underlying complex neurological disorders such as schizophrenia. Currently, I am the principal investigator of the group of "Neural Plasticity" of the "Neuroinflammation and cognitive impairment" department at the Prince Felipe Research Centre (Centro de Investigación Príncipe Felipe) since June 2019, where I supervise the work of one lab manager, two research assistants and two students.
Our principal goal is to dissect the neural circuit basis of neurological disorders employing mice as animal models of neuropsychiatric and neurodegenerative diseases.
Currently, we investigate the channelopathies underlying the early dysfunction of the prefrontal-hippocampal axis in neurological and neurodegenerative disorders. My work is currently supported by grants from the Spanish Ministry of Science and Innovation (JIN-Retos en investigación 2019) and by the Generalitat Valenciana (CIDEGenT Research Excellence Programme, Consellería de Educación from Generalitat Valenciana). Taking advantage of mouse models of Alzheimer´s disease (AD), we have started to disclose early functional alterations and molecular factors contributing to abnormal network activity within the cerebral cortex of animal models of AD.
People associated with the project as predoctoral research staff: 1
People associated with the project as technical support staff: 1